Pilocytic Astrocytoma: Anatomic, Pathological and Molecular Aspects

نویسندگان

  • Aline Paixao Becker
  • Cristovam Scapulatempo-Neto
  • Luciano Neder
  • Leila Chimelli
  • Rui M. Reis
چکیده

Brain tumors are rare neoplasms, however, they represent the second commonest cancer in childhood (the first being hemato-lymphoid neoplasms) and correspond to the main solid tumor in the pediatric context (ages 0-19 years) [1]. In this setting, gliomas, and particularly astrocytomas are the leading group. Pilocytic astrocytoma (PA) is the commonest brain tumor in the ages 5-14 years and the second in the age ranges 0-4 years and 15-19 years, although it represents about only 6% of all gliomas, according to the last Central Brain Tumors Registry (CBTRUS) Report [1]. PA affects males and females equally, and the main affected ages are 6 to 13 years-old, with 75% of cases occurring at this ages [2; 3].

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تاریخ انتشار 2013